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MedChemExpress
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Santa Cruz Biotechnology
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Merck & Co
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Federation of European Neuroscience Societies
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Promega
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BioShop
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Image Search Results
Journal: Frontiers in Immunology
Article Title: Soluble P2X7 Receptor Is Elevated in the Plasma of COVID-19 Patients and Correlates With Disease Severity
doi: 10.3389/fimmu.2022.894470
Figure Lengend Snippet: Treatment with ATP or Clostridium difficile toxin B induces the release of the P2X7 receptor. P2X7 receptor (left) or IL-1β (right) from human peripheral blood mononuclear cells from healthy individuals treated for 3 h with LPS (1.6 μg/ml) and then treated with ATP (5 mM) for 45 min or with Clostridium difficile toxin B (TcdB, 1 μg/ml) for 1 h. Each dot represents data from an independent individual.
Article Snippet: The different reagents used in this assay and their sources were ultrapure Escherichia coli lipopolysaccharide (LPS) serotype 0111:B4 (InvivoGen, SanDiego, CA, USA), adenosine 5′-triphosphate (ATP) from Sigma-Aldrich (St. Louis, MO, USA) and
Techniques:
Journal: Arteriosclerosis, Thrombosis, and Vascular Biology
Article Title: Statins Decrease Toll-Like Receptor 4 Expression and Downstream Signaling in Human CD14 + Monocytes
doi: 10.1161/01.atv.0000168410.44722.86
Figure Lengend Snippet: Figure 1. Effects of atorvastatin and simvastatin (SIM) on TLR4 mRNA expression in CD14 monocytes and reversion by meval- onate. Quantitative real-time PCR analysis of TLR4 in CD14 monocytes from 30 normocholesterolemic volunteers cultured with 1 mol/L ATOR, 10 mol/L SIM, or RPMI medium (control) for 24 hours. Addition of 1 mmol/L mevalonate completely inhib- ited the statin effect. Threshold cycle values were normalized for GAPDH expression and presented as meanSD. *P0.002 ATOR and SIM vs control and statin plus mevalonate.
Article Snippet:
Techniques: Expressing, Real-time Polymerase Chain Reaction, Cell Culture, Control, Inhibition